PulseExploreJournal ClubDebatesTrendingResearchersJournals
Instagram
HomeExploreJournal ClubTrending
Synapse
⌘+K
Synapse
April 29, 2026BJPsych Advances0 citationsOpen Access

Pharmacological treatment of severe behavioural and psychological symptoms of dementia: challenges and complexities

View Full Paper
NCNoel CollinsLLLianne LeungSir Charles Gairdner HospitalESElizabeth L. SampsonWhipps Cross University Hospital

Key Points

  • To critically explore challenges in treating severe behavioral and psychological symptoms of dementia with pharmacological methods.
  • Review of challenges in defining and treating severe BPSD
  • Analysis of prescribing practices for antipsychotics
  • Examination of clinical guidelines and legal frameworks
  • Identified complexities in the decision-making process for prescribing antipsychotics
  • Highlighted the legal and policy frameworks affecting care
  • Discussed the potential for palliative approaches in managing BPSD

Abstract

SUMMARY Severe behavioural and psychological symptoms of dementia (BPSD), associated with risk to self and others, often necessitate urgent intervention. Despite well-documented risks, antipsychotics remain frequently prescribed for these symptoms, reflecting complex influences on prescribing decisions. This review critically explores these challenging contexts, including difficulties in defining severe BPSD, conflations and limitations of current evidence and clinical guidelines, and legal and policy frameworks that shape care. This article advocates the adoption of alternative paradigms, notably palliative approaches, to address the considerable distress associated with severe BPSD, while remaining attentive to sociological critiques. Its broader aim is to stimulate discussion on the development of more humane and holistic models of care in this challenging area of older adult psychiatry.

Ask AI
Helpful
Bookmark
Share
View Full Paper

Cite This Study

Collins et al. (2026) studied this question.

synapsesocial.com/papers/69f154c0879cb923c4944eefhttps://doi.org/10.1192/bja.2026.10211
Ask AI
Helpful
Bookmark
Share
View Full Paper