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This method shows a novel one-pot synthesis of 9,10-diphenylhexahydro-acridine-1,8-dione with sulfamethoxazole, suggesting an effective catalytic approach.
Using silica sulfuric acid as a catalyst, a straightforward, effective, and environmentally acceptable method has been established for the synthesis of hexahydro‐acridine‐1,8‐dione integrating sulfamethoxazole under both standard heating and microwave‐assisted reaction conditions.
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Mohamed et al. (2026) studied this question.
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