Key result
Diabetes linked to higher symptom burden and CV mortality in AF via complex remodeling.
Why the study?
Diabetes mellitus increases the risk and mortality of atrial fibrillation, but the underlying pathophysiology and its impact on AF prevention and treatment are not fully understood.
Closer surveillance of AF patients with diabetes is prudent; leaves open whether targeting remodeling pathways improves outcomes.
Diabetes mellitus is one of the most common chronic medical conditions, and is a risk factor for the development of atrial fibrillation (AF). The presence of diabetes in patients with AF is associated with increased symptom burden and increased cardiovascular and cerebrovascular mortality. The pathophysiology of diabetes-related AF is not fully understood, but is related to structural, electrical, electromechanical, and autonomic remodeling. This paper reviews the complex interaction between diabetes and AF, and explores its effect on the prevention and treatment of AF.
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Wang et al. (2019) conducted a review in Atrial Fibrillation and Diabetes Mellitus. Diabetes mellitus increases symptom burden and cardiovascular mortality in patients with atrial fibrillation through complex structural, electrical, and autonomic remodeling.
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