Shows BAY 2413555 enables once-daily oral dosing without altering blood pressure, indicating potential to restore cardiac autonomic balance.
). With an overall technical profile compatible with once-daily oral administration in a phase 1 study, no apparent effects on blood pressure, and a mechanism that largely preserves autonomic regulatory capacity, BAY 2413555 could be the tool to finally study the restoration of autonomic balance.
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Vakalopoulos et al. (2024) studied this question.
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