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April 27, 2026Journal of Rheumatic DiseasesOpen Access

Identification of potential diagnostic biomarkers for osteoarthritis associated with glutamine metabolism

Liumei He Weiwei Wang Boyuan Qiu Siwen Tong Kangwei Yu Shouquan Zhu Chu Liu Zhixue Ou

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Key Points

The aim is to identify biomarkers associated with osteoarthritis that relate to glutamine metabolism.
Investigated biomarkers specific to glutamine-related pathways in osteoarthritis patients.
Used statistical analyses to assess the significance of identified biomarkers.
Identified several biomarkers significantly correlated with glutamine metabolism (p < 0.05).
Demonstrated that specific metabolic pathways are altered in osteoarthritis patients.

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Implication

Identifies diagnostic biomarkers related to glutamine metabolism in osteoarthritis, suggesting new insights for diagnosis.

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Cite This Study

He et al. (2026) studied this question.

synapsesocial.com/papers/69f19f74edf4b468248063f2 https://doi.org/10.4078/jrd.2026.0003

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Identification and validation of a glutamine metabolism-related gene signature as a diagnostic and therapeutic target in osteoarthritis through integrated multi-omics analysisOriginal Research · 2026 · 3 citations
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4Osteoarthritis pain inversely correlates with histidine and glutamine following CSF and serum profilingOriginal Research · 2026
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