Effectiveness of Oral Ondansetron on Revisits and Hospital Admissions in Children Aged 1–6 Years With Acute Gastroenteritii̇s: A Retrospective Cohort Study

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Oral ondansetron administration in children aged 1-6 years with acute gastroenteritis significantly reduces the rates of 7-day emergency department revisits and hospital admissions compared to no antiemetic treatment. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

Aydın Çelik; Mahmut Esat Tuluce; Nihat Cem Celebi

doi:10.24938/kutfd.1775040

April 27, 2026Kırıkkale Üniversitesi Tıp Fakültesi Dergisi

Effectiveness of Oral Ondansetron on Revisits and Hospital Admissions in Children Aged 1–6 Years With Acute Gastroenteritii̇s: A Retrospective Cohort Study

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Key Points

This study aims to evaluate the effects of oral ondansetron on emergency department revisit and hospital admission rates in children aged 1–6 years with acute gastroenteritis.
Retrospective cohort study including 339 children aged 1–6 years with acute gastroenteritis.
Participants were divided into ondansetron group (n=162) and control group (n=177).
Data on revisits, admissions, and fluid requirements were collected from medical records.
Emergency department revisit rate was 14% in the ondansetron group compared to 21% in the control group (p=0.036).
Hospital admission rates were lower in the ondansetron group at 2% versus 10% in the control group (exact p-value not fully provided in the abstract).

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Implication

Retrospective cohort study evaluates oral ondansetron's impact on revisits and admissions in young children, suggesting potential benefits.

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Çelik et al. (2026) studied this question.

synapsesocial.com/papers/69f1a033edf4b46824806d1a https://doi.org/10.24938/kutfd.1775040

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Effectiveness of Oral Ondansetron on Revisits and Hospital Admissions in Children Aged 1–6 Years With Acute Gastroenteritii̇s: A Retrospective Cohort Study

Key Points

No abstract yet

Implication

Discussion

Cite This Study

Effectiveness of Oral Ondansetron on Revisits and Hospital Admissions in Children Aged 1–6 Years With Acute Gastroenteritii̇s: A Retrospective Cohort Study

Key Points

No abstract yet

Implication

Discussion

Cite This Study

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