This article presents a critical–propositional analysis of Alexis Karpouzos’s Cosmology, Philosophy and Physics, published on Zenodo under the DOI https://doi.org/10.5281/zenodo.3364592, in confrontation with Vidamor Cabannas and Denivaldo Silva’s Theory of Objectivity (TO). The study examines Karpouzos’s interdisciplinary treatment of modern physics, quantum uncertainty, the observer problem, quantum vacuum, information, quantum logic, string theory, spacetime geometry, entropy, self-organized systems, Prigogine’s irreversibility, ancient knowledge, and the metaphysical question of nothingness. The article argues that Karpouzos’s cosmological philosophy offers a fertile field of dialogue with the Theory of Objectivity, especially because both frameworks reject naïve materialism, emphasize relationality, recognize the insufficiency of classical determinism, and assign a central role to information in the constitution of cosmic reality. At the same time, the study identifies important tensions: Karpouzos often moves through poetic, spiritual, and metaphysical language, whereas the Theory of Objectivity requires modal axiomatic necessity, objective boundaries between elements, phenomenic structure, Inductive Effects, cosmogenic sequencing, and a more precise definition of transcendence. The central proposal is that Karpouzos’s holistic universe may be reinterpreted, under the modal discipline of the Theory of Objectivity, as an informational–relational cosmos in which the transcendent element is not an indeterminate spiritual consciousness, but the knowledge or information produced in atomic relations, equivalent to atomic radiations. The article concludes that Karpouzos’s work achieves a high degree of dialogue with the TO, while requiring formal correction through the axioms, phenomenic elements, Inductive Effects, cosmological Eras, and cosmogenic theorem of the Theory of Objectivity. This analytical text received analytical support from ChatGPT. Keywords: Theory of Objectivity; Vidamor Cabannas; Alexis Karpouzos; Cosmology; Philosophy of Physics; Quantum Information; Quantum Vacuum; Modal Ontology; Inductive Effects; Atomic Radiation; Transcendence; Prigogine; Self-Organization; Spacetime Geometry; Observer Problem; Cosmogenesis; Nothingness; Informational Totality.
Cabannas et al. (Mon,) studied this question.