Why the study?
The role of the accessory pathway and the mode of onset of atrial fibrillation in patients with Wolff-Parkinson-White syndrome remained to be evaluated.
What is the mode of onset of atrial fibrillation and the role of the accessory pathway in patients with Wolff-Parkinson-White syndrome?
What is the mode of onset of atrial fibrillation and the role of the accessory pathway in patients with Wolff-Parkinson-White syndrome?
In patients with Wolff-Parkinson-White syndrome, atrial fibrillation typically begins with rapid atrial tachycardia at a high right atrial site, and vulnerability to AF is associated with specific electrophysiologic properties including longer PA interval and shorter atrial and accessory pathway refractory periods.
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Atrial factors beyond accessory pathways may drive AF in WPW; leaves open substrate research before practice change.**[[1]](https://www.jacc.org/doi/10.
Fujimura et al. (1990) studied this question.
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