Role of calcium ions in transient inward currents and aftercontractions induced by strophanthidin in cardiac Purkinje fibres.
Population
Cardiac Purkinje fibres
Design
Preclinical
Authors
Discussion
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Member takes
Implication
Links calcium oscillations to aftercontractions in Purkinje fibers; leaves open human arrhythmia relevance.
Structured PICO
P
Population
Cardiac Purkinje fibres
I
Intervention
Strophanthidin and varying extracellular calcium concentrations
O
Outcome
Transient inward current (TI) and aftercontractionssurrogate
Transient inward currents and aftercontractions induced by strophanthidin in cardiac Purkinje fibres are driven by oscillatory release of intracellular calcium.
Cite This Study
Kass et al. (1978) studied this question.