What type of study is this?

This is a Cohort Study study (also classified as: Mixed-Methods).

What question did this study set out to answer?

This audit aims to identify predictors of difficult-to-treat rheumatoid arthritis.

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This audit aims to identify predictors of difficult-to-treat rheumatoid arthritis.
Retrospective analysis of patient data from a single biologic registry.
Included over 1700 rheumatoid arthritis patients on biologic drugs.
Used univariate and multivariate analyses to identify predictors of D2T RA.
40.8% of patients met criteria for difficult-to-treat rheumatoid arthritis.
Erosive disease was identified as a significant predictor in multivariate analysis.
Significant associations found with comorbidities and smoking status.

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Retrospective audit of patient data reveals comorbidities and disease activity impacts patient outcomes in D2T rheumatoid arthritis.

Ghosh et al. (2026) studied this question.

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