Effect of lanthanide (III) complexation on the radiolytic stability of Macropa

Alexandre Gaspar; Julie Hostier; Dominique Guillaumont; Claude Berthon; Xavier Hérès; Briscese Luca; Bertrand Kuhnast; Laurence Berthon

doi:10.1039/d6dt00671j

January 1, 2026Dalton TransactionsOpen Access

Effect of lanthanide (III) complexation on the radiolytic stability of Macropa

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Key Points

To assess how lanthanide complexation affects the radiolytic stability of Macropa.
Examined the interactions of lanthanide ions with Macropa under radiolytic conditions.
Analyzed stability performance of Macropa as a chelator for radionuclides.
Evaluated potential for use in nuclear medicine therapies and diagnoses.
Lanthanide complexation significantly enhances the radiolytic stability of Macropa.
The improved stability suggests better performance of Macropa as a chelator in nuclear settings.

Implication

Findings demonstrate improved radiolytic stability of chelators in nuclear medicine, suggesting enhanced use of radionuclides.

Abstract

The growing use of radionuclides in nuclear medicine for therapy and diagnosis requires the development of chelators that combine high complexation performance with strong radiolytic stability. Macropa, an ether-crown ligand,...

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Cite This Study

Gaspar et al. (2026) studied this question.

synapsesocial.com/papers/69f2a4f18c0f03fd67764146 https://doi.org/10.1039/d6dt00671j

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Effect of lanthanide (III) complexation on the radiolytic stability of Macropa

Key Points

Implication

Abstract

Discussion

Cite This Study

Effect of lanthanide (III) complexation on the radiolytic stability of Macropa

Key Points

Implication

Abstract

Discussion

Cite This Study

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