June 1, 2008Journal of the CardioMetabolic Syndrome
Impact of Cardiac Rehabilitation on Coronary Risk Factors, Inflammation, and the Metabolic Syndrome in Obese Coronary Patients
Why the study?
Does formal cardiac rehabilitation and exercise training improve coronary risk factors, inflammation, and metabolic syndrome in obese patients with coronary heart disease?
Structured PICO
Does formal cardiac rehabilitation and exercise training improve coronary risk factors, inflammation, and metabolic syndrome in obese patients with coronary heart disease?
P
Population
235 consecutive patients with coronary heart disease (CHD), including a subgroup analysis of 72 lean patients (BMI <25 kg/m2) and 73 obese patients (BMI >=30 kg/m2)
I
Intervention
Formal cardiac rehabilitation and exercise training (CRET) programs
C
Comparator
Baseline (pre-intervention) and lean patients (BMI <25 kg/m2)
O
Outcome
Changes in obesity indices (weight, BMI, percentage of fat), peak exercise capacity, HDL cholesterol, C-reactive protein, behavioral characteristics, quality of life, and prevalence of metabolic syndromesurrogate
Cardiac rehabilitation and exercise training significantly improve obesity indices, exercise capacity, lipid profiles, inflammation, and quality of life in obese patients with coronary heart disease.
Authors
Discussion
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Implication
Supports CRET benefits in obese CHD patients; leaves open need for RCTs to confirm causality before practice change.
Cite This Study
Lavie et al. (2008) studied this question.