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April 30, 2026Nature CommunicationsOpen Access

CFTR mediates Cl- transport in osteocytes to sustain cell viability and skeletal homeostasis

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Authors

PHPeijie HuWDWanting DuMCMuyan Chu

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Overview

Randomized trial investigates chloride transport's role in osteocyte viability, suggesting implications for bone health.

Key Points

  • The research aims to explore how CFTR influences chloride transport and its effect on osteocyte health and bone stability.
  • Examined the role of CFTR in osteocyte chloride transport
  • Assessed the impact on cell viability
  • Analyzed skeletal homeostasis metrics
  • CFTR activity significantly enhances chloride transport in osteocytes
  • Increased chloride transport correlates with improved cell viability
  • Disruption of CFTR impairs skeletal homeostasis

Cite This Study

Hu et al. (2026) studied this question.

synapsesocial.com/papers/69f2f0991e5f7920c6386ccbhttps://doi.org/10.1038/s41467-026-72349-0
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