This work aims to develop a protocol for synthesizing nitrocinnamonitriles from nitrotoluenes.
Developed a chemical synthesis protocol for nitrocinnamonitriles.
Tested compatibility with various substituted aromatic and heteroaromatic systems.
Explored the reaction conditions for optimal yields.
Demonstrated successful synthesis of nitrocinnamonitriles from nitrotoluenes.
Showed compatibility with polysubstituted aromatic rings and broad heteroaromatic systems.
Resumen
to the nitro substituent on the nitrotoluene scaffold. Furthermore, it was compatible with polysubstituted aromatic rings and could be readily extended to a broad range of heteroaromatic systems.