Asymmetry in a Symmetric Host: Microbiota Dysbiosis Underlying Unilateral Fungal Rhinosinusitis

Yen‐Ting Lu

doi:10.7248/jjrhi.65.76

January 1, 2026Nihon Bika Gakkai Kaishi (Japanese Journal of Rhinology)Open Access

Asymmetry in a Symmetric Host: Microbiota Dysbiosis Underlying Unilateral Fungal Rhinosinusitis

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Key Points

This research aims to explore the relationship between microbiota dysbiosis and unilateral fungal rhinosinusitis.
Analysis of fungal colonization patterns in patients with unilateral rhinosinusitis.
Examination of the immune response in symmetric hosts.
Identified distinct microbial profiles associated with unilateral fungal colonization.
Observed localized inflammation in response to fungal presence despite symmetrical immune traits.

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Implication

Demonstrates microbiota dysbiosis related to unilateral fungal rhinosinusitis, implying a need for targeted treatment.

Abstract

Fungal rhinosinusitis (FRS) is a distinct and typically unilateral phenotype of chronic rhinosinusitis (CRS), characterized by localized fungal colonization and inflammation despite a symmetrical host immune system.

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Cite This Study

Yen‐Ting Lu (2026) studied this question.

synapsesocial.com/papers/69f2f1471e5f7920c6387056 https://doi.org/10.7248/jjrhi.65.76

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Asymmetry in a Symmetric Host: Microbiota Dysbiosis Underlying Unilateral Fungal Rhinosinusitis

Key Points

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

Asymmetry in a Symmetric Host: Microbiota Dysbiosis Underlying Unilateral Fungal Rhinosinusitis

Key Points

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

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