Pyogenic Liver Abscess and Pylephlebitis Secondary to Klebsiella pneumoniae

Pylephlebitis, septic thrombosis of the portal venous system secondary to Klebsiella pneumoniae liver abscess is a rare and potentially life-threatening condition. We present an unusual case of suppurative thrombophlebitis hepatic vein thrombosis in a healthy male who presented with unspecified abdominal pain, fever, and vomiting. He was managed promptly with upfront antimicrobial therapy, and anticoagulation led to an uneventful recovery.