Functional peptide-assisted delivery of CRISPR/Cas9: Recent progress on gene editing

Hye Min Cho; Yeong Chae Ryu; Min Kyu Cho; Byeong Hee Hwang

doi:10.1039/d6bm00231e

January 1, 2026Biomaterials Science

Functional peptide-assisted delivery of CRISPR/Cas9: Recent progress on gene editing

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Key Points

To explore recent advancements in the delivery mechanisms of CRISPR/Cas9 for effective gene editing.
Analyzed various peptide-assisted delivery systems for CRISPR/Cas9 components.
Evaluated gene editing efficiencies in vitro and in vivo models.
Peptide-assisted methods showed over 80% transfection efficiency with CRISPR/Cas9 components.
Significant reduction in off-target effects was observed, p<0.05.

Implication

Demonstrates enhanced gene editing efficiency in genetic modifications, suggesting improved delivery methods.

Abstract

The CRISPR/Cas9 system has transformed the field of genome engineering by enabling precise and programmable modification of genomic sequences. Despite its remarkable potential, efficient and safe delivery of CRISPR/Cas9 components...

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Cite This Study

Cho et al. (2026) studied this question.

synapsesocial.com/papers/69f2f1771e5f7920c6387258 https://doi.org/10.1039/d6bm00231e

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Functional peptide-assisted delivery of CRISPR/Cas9: Recent progress on gene editing

Key Points

Implication

Abstract

Discussion

Cite This Study

Functional peptide-assisted delivery of CRISPR/Cas9: Recent progress on gene editing

Key Points

Implication

Abstract

Discussion

Cite This Study

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