Secondary Colonic Adenocarcinoma After Continent Cutaneous Urinary Diversion a.m. Lundiana—An Aggressive Disease Entity With High Risk of Locally Advanced Disease and Metastases

Introduction We herein report two patients developing secondary adenocarcinomas arising in colonic segments used for urinary diversion a.m. Lundiana in a population‐based series 16 and 27 years after cystectomy, respectively. Case Presentation Following initial partial resection of the pouch, both patients experienced local recurrence; one subsequently developed distant metastases and died from secondary adenocarcinoma, whereas the other patient underwent extirpation of the pouch and re‐diversion with an ileal conduit. Conclusions Based on these patients, upfront radical surgery would have been a more effective treatment. In this patient population, clinical awareness but not screening for secondary adenocarcinomas seems to be the most appropriate strategy.