Shows circulating RNAs aid disease diagnosis and prognosis, suggesting new diagnostic pathways.
The development of malignant tumors from healthy tissues is associated with profound changes in expression profiles of a large number of mRNAs, miRNAs and lncRNAs. These changes on the one hand permit insights into the biology of individual tumors; on the other hand, tumor-derived RNAs can also be detected in circulating blood and serve as specific markers for differential diagnosis and patient prognosis.
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