Why the study?
Is there an association between invasively measured coronary microvascular dysfunction and CMRI parameters of right ventricular structure and function in patients with suspected INOCA?
Is there an association between invasively measured coronary microvascular dysfunction and CMRI parameters of right ventricular structure and function in patients with suspected INOCA?
In patients with suspected INOCA, there is no significant concurrent relationship between invasively measured coronary microvascular dysfunction and CMRI-derived right ventricular structure or function.
Answers are grounded in this paper and cite their sources.
No RV-microvascular correlation in suspected INOCA; leaves open causal or longitudinal relationships.
, RV ejection fraction was 62.7%±5.6% and RV longitudinal strain was -27.2%±3.5%. We found no significant correlation between RV parameters and coronary microvascular function. This is the first study to report associations between invasively measured CMD and CMRI parameters of RV structure and function among patients with suspected INOCA. Despite a large sample size, we found no significant relationship between RV structure or function and CMD. These results suggest that RV abnormalities do not precede and are not concurrent with CMD in suspected INOCA participants. Longitudinal prospective studies are needed to evaluate if RV deterioration may occur later during the course of CMD and among patients with HFpEF.
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Paquin et al. (2025) studied this question.
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