September 1, 1992European Heart Journal

A possible mechanism for pacemaker-induced T-wave changes

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Why the study?

Does ventricular pacing produce myocardial ischemia and T-wave changes in patients with bradyarrhythmias?

Population

10 patients with various bradyarrhythmias taking no medication

Comparison

Ventricular pacing at a physiological rate for… vs Baseline (before VP) and after cessation of VP

Design

Case_series

Follow-up

up to 1 month after ceasing VP

Authors

LFLianting FuInternational Peace Maternity & Child Health Hospital KIKenji ImaiTeikyo Heisei University AOA OkabeCardiovascular Institute Hospital

Discussion

Member takes

Implication

Chronic VP may induce transient ischemia explaining post-pacing T-wave changes; hypothesis-generating in this case series and needs prospective validation.

Structured PICO

Does ventricular pacing produce myocardial ischemia and T-wave changes in patients with bradyarrhythmias?

Population

10 patients with various bradyarrhythmias taking no medication

Intervention

Ventricular pacing (VP) at a physiological rate for 14 days or more

Comparator

Baseline (before VP) and after cessation of VP

Outcome

Changes in body surface potential mapping (BSM) and resting thallium-201 myocardial scintigraphy (T1-SC)surrogate

Chronic ventricular pacing may induce transient myocardial ischemia that persists after pacing cessation, explaining post-pacing T-wave inversions.

Cite This Study

Fu et al. (1992) studied this question.

synapsesocial.com/papers/69f3edd9dc238f81977994bc https://doi.org/10.1093/oxfordjournals.eurheartj.a060333

Topics

Women and heart disease

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Implication

Chronic VP may induce transient ischemia explaining post-pacing T-wave changes; hypothesis-generating in this case series and needs prospective validation.