Homologation of Isoindoles: 2- N,N′ -Bis( tert -butoxycarbonyl)amidino-2 H -benzo f isoindole and 2 H -naphtho2,3- f isoindole

Puntos clave

• The aim is to synthesize isoindoles and evaluate their chemical reactivity and stability.
• Multistep synthesis of isoindoles was performed.
• Reactivity toward various dienophiles was studied.
• Instability of isoindoles in solution was assessed.
• Successfully synthesized two isoindoles: 2-[N,N'-Bis(tert-butoxycarbonyl)amidino]-2H-benzo[f]isoindole and 2H-naphtho[2,3-f]isoindole.
• Notable reactivity observed with specific dienophiles.
• Established instability in solution for the synthesized isoindoles.