Stereospecific N-Glycosylation Strategy for β-N-Glycoside Synthesis via Base Catalysis.

Key Points

• The central aim is to develop a stereospecific N-glycosylation method for synthesizing β-glycosides.
• Utilized base catalysis for glycosylation.
• Achieved high yields and stereocontrol without traditional stereodirecting groups.
• Demonstrated late-stage modification on complex drug molecules.
• Achieved high yields in β-glycoside synthesis.
• Exhibited outstanding β-stereocontrol without the need for stereodirecting groups.
• Showed potential for modifying complex drug structures effectively.