Case reports nodular fasciitis misdiagnosed as sarcoma in a male, suggesting imaging features can prevent unnecessary surgery.
Nodular fasciitis rarely arises from the masseter muscle and is frequently misdiagnosed as soft tissue sarcoma. A 43-year-old male presented with a rapidly enlarging, painless swelling below the right mandibular angle over 2 months. Clinical examination revealed a firm, mobile mass without skin fixation or lymphadenopathy. Ultrasound and magnetic resonance imaging were performed, followed by fine-needle aspiration cytology and excisional biopsy. Ultrasound demonstrated a well-defined, hypoechoic lobulated lesion (23 × 13 × 8 mm) within the superficial masseter, showing mild internal vascularity and no bone involvement. Magnetic resonance imaging revealed an iso- to slightly hypointense T1 signal, hyperintense T2/ short tau inversion recovery signal, and homogeneous postcontrast enhancement with smooth margins, features suggestive of a benign myofibroblastic lesion. Excisional biopsy confirmed the diagnosis of nodular fasciitis. This case indicates that masseteric nodular fasciitis, a rare benign lesion, may present with imaging features of small size, smooth margins, homogeneous enhancement, and mild vascularity in the context of trauma history. Recognition of this self-limited myofibroblastic proliferation can prevent unnecessary radical surgery and guide conservative management.
No takes yet. Share an insight, caveat, or question.
Joni et al. (2026) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: