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Cross-sectional analysis reveals that psychedelic users have greater self-compassion and life satisfaction, indicating therapeutic potential.
Emerging evidence suggests psychedelic-assisted therapies ameliorate symptoms of psychopathology. However, less is known about how psychedelics influence positive psychological functioning (e.g., compassionate love, self-compassion, and life satisfaction). These constructs may be relevant in understanding how psychedelics exert their therapeutic effects, as they are central to both intra- and interpersonal well-being, and may function as protective factors against psychopathology. In a cross-sectional sample ( N = 984), we compared psychedelic-naive individuals ( n = 169) to former ( n = 178) and current ( n = 637) psychedelic users on compassionate love, self-compassion, life satisfaction, and lifetime mystical-type experiences (MTEs). After controlling for confounding variables, current and former users reported significantly greater compassionate love, self-compassion, life satisfaction, and lifetime MTEs than psychedelic-naive individuals. Relative to former users, current psychedelic users reported significantly greater self-compassion, life satisfaction, and lifetime MTEs, but not compassionate love. Across all groups, lifetime MTEs were positively associated with positive psychological functioning, suggesting that relationships between MTEs and psychological functioning may not be restricted to psychedelic use. Although limited by self-reporting biases, a cross-sectional design, and a homogenous sample, our findings suggest psychedelic use and MTEs are associated with positive psychological functioning, warranting further examination of these psychological constructs in clinical trials.
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Mallard et al. (2026) studied this question.
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