Limosilactobacillus fermentum ANC4 (KCTC 15072BP) Mitigates Dexamethasone-Induced Muscle Atrophy and Improves Overall Skeletal Muscle Function.

Seong‐Min Hong; Jinho Park; Su-Hyun Kim; Ahyoung Hwang; Eun Sung Jung; Donghyun Cho; Yosep Ji; S H Kim; Choong-Hwan Lee

doi:10.4014/jmb.2603.03025

April 28, 2026

Limosilactobacillus fermentum ANC4 (KCTC 15072BP) Mitigates Dexamethasone-Induced Muscle Atrophy and Improves Overall Skeletal Muscle Function.

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Key Points

The aim is to investigate the ability of ANC4 to prevent muscle atrophy and improve skeletal muscle function.
Intervention with Limosilactobacillus fermentum ANC4 in a controlled setting.
Assessment of muscle atrophy markers and overall muscle function pre- and post-intervention.
ANC4 significantly reduced muscle atrophy markers compared to the control group.
Improvements in muscle function were observed with ANC4, indicating its therapeutic potential.

Implication

Shows ANC4 improves skeletal muscle function in muscle atrophy, suggesting therapeutic benefits.

Abstract

ANC4 prevents muscle atrophy by balancing catabolic signaling and myogenic repair, highlighting its potential as a probiotic or postbiotic therapy for preserving muscle mass and function.

Discussion

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Cite This Study

Hong et al. (2026) studied this question.

synapsesocial.com/papers/69f443cb967e944ac5566d54 https://doi.org/10.4014/jmb.2603.03025

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Limosilactobacillus fermentum ANC4 (KCTC 15072BP) Mitigates Dexamethasone-Induced Muscle Atrophy and Improves Overall Skeletal Muscle Function.

Key Points

Implication

Abstract

Discussion

Cite This Study

Limosilactobacillus fermentum ANC4 (KCTC 15072BP) Mitigates Dexamethasone-Induced Muscle Atrophy and Improves Overall Skeletal Muscle Function.

Key Points

Implication

Abstract

Discussion

Cite This Study

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