Methylome profiles reveal gene regulation in serogroup B Neisseria meningitidis, suggesting implications for meningitis treatment.
serogroup B is a major cause of meningitis and septicemia. Here, we report PacBio HiFi single-molecule real-time (SMRT) methylomics data sets for strains MC58, B6116/77, and M0579. These strains encode the phase-variable DNA methyltransferases ModA11, ModA12, and ModD1, respectively, which are epigenetic regulators pivotal to meningococcal pathogenicity.
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Ascari et al. (2026) studied this question.
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