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Demonstrates the role of ferroptosis and treatment efficacy in viral encephalitis, suggesting new therapeutic approaches.
pathway. Notably, treatment with the ferroptosis inhibitor deferoxamine effectively mitigates PRV-induced ferroptosis, reduces viral titers in mouse brains, and alleviates viral encephalitis. In conclusion, our study reveals the critical role of ferroptosis in PRV-induced viral encephalitis, providing therapeutic insights for treating PRV-associated neurological diseases.
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Sun et al. (2026) studied this question.
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