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May 1, 2026IJEM Case ReportsOpen Access

Unveiling multiple endocrine neoplasia type 2A through cutaneous lichen amyloidosis: A rare clinical association

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Authors

SMSachin ModiSMSantosha ManthaANAmit Nachankar

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Overview

Case report uncovers cutaneous lichen amyloidosis as a marker for multiple endocrine neoplasia type 2A, enabling timely diagnosis and management.

Key Points

  • The aim is to highlight the association between cutaneous lichen amyloidosis and multiple endocrine neoplasia type 2A.
  • Case report of a 26-year-old female with a pruritic skin lesion diagnosed as cutaneous lichen amyloidosis.
  • Genetic testing confirmed a RET Cys634Tyr mutation associated with MEN 2A.
  • The patient underwent bilateral adrenal-sparing adrenalectomy, total thyroidectomy, and parathyroidectomy.
  • CLA was identified as a significant marker for the early detection of MEN 2A.
  • Successful surgical intervention improved the patient's condition and prevented further complications.
  • Early recognition facilitated timely genetic counseling for the patient and family.

Cite This Study

Modi et al. (2026) studied this question.

synapsesocial.com/papers/69f44464967e944ac55675cbhttps://doi.org/10.4103/ijemcr.ijemcr_47_25
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The Changing Face of Multiple Endocrine Neoplasia 2A: From Symptom-Based to Preventative Medicine2023 · 33 citations
  2. 2Roles of the RET Proto-oncogene in Cancer and Development2020 · 85 citations
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  5. 5Multiple endocrine neoplasia type 2A with cutaneous lichen amyloidosis2020 · 13 citations