Key result
Adding LVDD to EuroSCORE II, STS, and MAGGIC increases postoperative complication AUC by ~0.08.
Why the study?
The universal prognostic value of adding left ventricular diastolic dysfunction to clinical risk scores like EuroSCORE II, STS, and MAGGIC in patients undergoing CABG had not been evaluated.
Does the addition of left ventricular diastolic dysfunction (LVDD) assessment improve the prognostic accuracy of EuroSCORE II, STS, and MAGGIC models for postoperative complications in patients undergoing elective CABG?
Cohort (n=178)
Does the addition of left ventricular diastolic dysfunction (LVDD) assessment improve the prognostic accuracy of EuroSCORE II, STS, and MAGGIC models for postoperative complications in patients undergoing elective CABG?
Answers are grounded in this paper and cite their sources.
The addition of echocardiographic left ventricular diastolic dysfunction assessment significantly improves the prognostic accuracy of standard risk models (EuroSCORE II, STS, MAGGIC) for predicting postoperative complications in patients undergoing elective CABG.
Objective. To evaluate the universal prognostic value of left ventricular diastolic dysfunction (LVDD) when added to various clinical risk scores (EuroSCORE II, STS, MAGGIC) in patients undergoing coronary artery bypass grafting (CABG). Materials and Methods. The study included 178 patients with coronary artery disease who underwent elective CABG. Clinical, echocardiographic, and functional parameters were analyzed, including the assessment of left ventricular diastolic function. EuroSCORE II, STS, and MAGGIC risk scores were calculated for all patients. The prognostic value of the models was assessed using ROC analysis (AUC), DeLong test, risk reclassification indices (NRI, IDI), and Decision Curve Analysis. Results. Left ventricular diastolic dysfunction was an independent predictor of postoperative complications. The addition of LVDD to the EuroSCORE II, STS, and MAGGIC models significantly improved their discriminative ability (ΔAUC = 0.07–0.08; p < 0.05 for all models). NRI and IDI indices demonstrated a statistically significant improvement in risk stratification across all models. Decision Curve Analysis showed increased clinical usefulness of the combined models across a wide range of risk thresholds. Conclusion. LVDD is a universal functional risk modifier that improves the prognostic accuracy of various clinical models. Inclusion of left ventricular diastolic function assessment in preoperative risk stratification algorithms for CABG may significantly improve clinical decision-making.
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I.K. et al. (2026) conducted a cohort in coronary artery disease (n=178). Addition of left ventricular diastolic dysfunction (LVDD) to risk scores vs. EuroSCORE II, STS, and MAGGIC models alone was evaluated on discriminative ability for postoperative complications (ΔAUC 0.07-0.08, p=<0.05). Adding left ventricular diastolic dysfunction to EuroSCORE II, STS, and MAGGIC models significantly improved their discriminative ability for postoperative complications (ΔAUC = 0.07-0.08; p < 0.05).
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