Why the study?
Percutaneous debulking is a treatment option for tricuspid valve infective endocarditis, but the outcomes of this approach are less well known.
Does percutaneous vegetation debulking improve clearance of blood cultures and safety outcomes compared to published surgical outcomes in patients with tricuspid valve infective endocarditis?
Does percutaneous vegetation debulking improve clearance of blood cultures and safety outcomes compared to published surgical outcomes in patients with tricuspid valve infective endocarditis?
Percutaneous debulking is a feasible, effective, and safe option for treating tricuspid valve infective endocarditis refractory to medical therapy.
May support percutaneous debulking in refractory tricuspid endocarditis; leaves open prospective trials versus surgery.
BACKGROUND: In patients with tricuspid valve infective endocarditis, percutaneous debulking is a treatment option. However, the outcomes of this approach are less well known. METHODS: We performed a retrospective analysis of all patients who underwent percutaneous vegetation debulking for tricuspid valve infective endocarditis from August 2020 to November 2022 at a large academic tertiary care public hospital. The primary efficacy outcome was procedural success defined by clearance of blood cultures. The primary safety outcome was any procedural complication. For the composite outcome of in-hospital mortality or heart block, outcomes were compared (sequential noninferiority and superiority) with published surgical outcomes data. CONCLUSIONS: Percutaneous debulking is feasible, effective, and safe in treating patients with tricuspid valve infective endocarditis refractory to medical therapy.
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Zhang et al. (2023) studied this question.
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