Prognostic Value of Vasodilator Stress Cardiac Magnetic Resonance Imaging
Why the study?
Stress CMR is not widely used in current clinical practice, and its ability to predict patient mortality was unknown.
Does an abnormal vasodilator stress CMR predict all-cause mortality in patients with known or suspected CAD?
Population
9151 patients with known or suspected CAD undergoing clinical evaluation of myocardial ischemia
Comparison
Abnormal vs normal stress CMR examination
Design
Multicenter observational study across 7 hospitals
Follow-up
Median 5.0 years
Authors
Discussion
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Member takes
Implication
Supports stress CMR for mortality risk stratification in CAD; extends observational data but leaves open prospective validation.
Structured PICO
Does an abnormal vasodilator stress CMR predict all-cause mortality in patients with known or suspected CAD?
P
Population
9,151 patients with known or suspected coronary artery disease (CAD) undergoing clinical evaluation of myocardial ischemia, median age 63, 55% male.
I
Intervention
Abnormal clinical vasodilator stress cardiac magnetic resonance imaging (CMR)
C
Comparator
Normal clinical vasodilator stress CMR
O
Outcome
All-cause patient mortality assessed using the US Social Security Death Indexhard clinical
In a large real-world cohort, an abnormal vasodilator stress CMR was strongly associated with increased all-cause mortality, demonstrating its prognostic value in patients with known or suspected CAD.
Cite This Study
Heitner et al. (2019) studied this question.