Why the study?
What are the main features of FDG uptake on PET/CT in patients with noninfected prosthetic heart valves?
What are the main features of FDG uptake on PET/CT in patients with noninfected prosthetic heart valves?
Noninfected prosthetic heart valves frequently display homogeneous FDG uptake on PET/CT that remains steady over time, highlighting the need for caution and attention to uptake patterns when diagnosing prosthetic valve endocarditis.
May confound PVE diagnosis on PET/CT; leaves open optimal pattern-based criteria.
BACKGROUND: F-Fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) has been recently acknowledged as a diagnostic tool for prosthetic valve endocarditis, but its specificity is limited by uptake on noninfected valves. The objective of this study was to outline the main features of FDG uptake on PET/CT in patients with noninfected prosthetic heart valve (PHV). METHODS AND RESULTS: =0.01) and in patients with vasculitis than in those referred for other indications. The uptake intensity did not differ before and 3 months after valve replacement. CONCLUSIONS: Noninfected PHVs frequently display homogeneous FDG uptake, which remains steady over time. Caution is, therefore, needed when interpreting FDG PET/CT in suspected prosthetic valve endocarditis, with specific attention to uptake pattern.
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Mathieu et al. (2017) studied this question.
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