Why the study?
Clinically, regurgitant orifice shapes may be noncircular, and the influence of orifice shape and machine factors on the proximal isovelocity surface area method was unclear.
Does the hemi-elliptic model for PISA accurately estimate volume flow rate for noncircular orifices compared to a hemispheric model in vitro?
Population
In vitro flow experiments evaluating orifice shapes (n = 226) and machine factors (n = 83)
Comparison
Hemi-elliptic model vs hemispheric model across noncircular orifice shapes
Design
In vitro experimental study
Authors
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May improve quantification of valvular regurgitation; leaves open validation beyond planar circular orifices.**[[1]](https://www.sciencedirect.
Does the hemi-elliptic model for PISA accurately estimate volume flow rate for noncircular orifices compared to a hemispheric model in vitro?
A hemi-elliptic model for PISA provides more accurate volume flow rate estimates for noncircular orifices than a hemispheric model in vitro.
Utsunomiya et al. (1991) studied this question.
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