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May 2, 2026Open Access

Formulation Development and Evaluation of Orodispersible Doxofylline Tablets for Rapid Bronchodilation in Asthma Management

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Authors

AYAnuj YadavDYDr. Akash YadavDJDr. Dinesh Kumar Jain

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Overview

Randomized trial evaluates the efficacy of fast-dissolving doxofylline tablets in asthma management, suggesting a patient-friendly approach.

Key Points

  • The aim is to develop and evaluate fast-dissolving doxofylline tablets for improved asthma management.
  • Developed 400 mg doxofylline fast-dissolving tablets using direct compression under Quality by Design framework.
  • Conducted excipient compatibility assessments and preformulation characterization.
  • Performed superdisintegrant optimization and validated with UV spectrophotometry and RP-HPLC.
  • Demonstrated rapid dissolution rates suitable for acute respiratory distress scenarios.
  • Validated analytical methods adhere to ICH guidelines, ensuring regulatory compliance.

Cite This Study

Yadav et al. (2026) studied this question.

synapsesocial.com/papers/69f5949771405d493afff620https://doi.org/10.5281/zenodo.19913031
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