Demonstrates a new method for selenylation of alcohols, suggesting efficient synthesis pathways.
-promoted dehydroxypropylative selenylation of tertiary acyclic alcohols with diselenides has been developed for constructing unsymmetrical monoselenides. This protocol enables direct C-C bond cleavage and concomitant C-Se bond formation without the need for an additional photocatalyst. The reaction exhibits a broad substrate scope across various diselenides and alcohols and is amenable to gram-scale synthesis. Mechanistic studies support a radical pathway initiated through ligand-to-metal charge transfer (LMCT) upon light irradiation.
No takes yet. Share an insight, caveat, or question.
Guo-min et al. (2026) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: