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Synapse
May 2, 20260 citations

Retracted Rosiglitazone exerts neuroprotective effects via the suppression of neuronal autophagy and apoptosis in the cortex following traumatic brain injury.

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JYJunchao YaoKZKebin ZhengXZXi Zhang

Key Points

  • To investigate the neuroprotective effects of rosiglitazone following traumatic brain injury.
  • Identified duplications in data across several figures
  • No response from authors regarding data concerns
  • Paper retracted due to lack of confidence in the findings.
  • Editor retracts the paper due to concerns about data integrity
  • No valid data to support the claimed effects of rosiglitazone
  • Apology issued to readers for the confusion caused.

Abstract

. In view of the fact that so many instances of the duplication of data within several of the figures in the above paper were identified, the Editor has decided that this paper should be retracted from the Journal on account of a lack of confidence in the data. The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a reply. The Editor apologizes to the readership for any inconvenience caused. Molecular Medicine Reports 12: 6591‑6597, 2015; DOI: 10.3892/mmr.2015.4292.

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Cite This Study

Yao et al. (2026) studied this question.

synapsesocial.com/papers/69f594fc71405d493afffdfbhttps://doi.org/10.3892/mmr.2026.13894
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Retraction: Rosiglitazone exerts an anti-depressive effect in unpredictable chronic mild-stress-induced depressive mice by maintaining essential neuron autophagy and inhibiting excessive astrocytic apoptosis2025
  2. 2[Retracted] Sevoflurane attenuates brain damage through inhibiting autophagy and apoptosis in cerebral ischemia‑reperfusion rats2025
  3. 3RETRACTION : Glycogen Synthase Kinase 3β ( GSK3β ) Mediates 6‐Hydroxydopamine‐Induced Neuronal Death2026
  4. 4[Retracted] Role of miR‑146a in human chondrocyte apoptosis in response to mechanical pressure injury in vitro2026
  5. 5Rosiglitazone regulates astrocyte polarization and neuroinflammation in a PPAR-γ dependent manner after experimental traumatic brain injury2024 · 14 citations