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September 23, 2015Veterinary Clinical Pathology

Biologic variability and correlation of platelet function testing in healthy dogs

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Population

9 healthy dogs

Design

Preclinical

Follow-up

4 consecutive weeks

Authors

SBShauna L. BloisSLSean LangRWR. Darren Wood

Discussion

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Overview

High canine platelet test variability cautions against population references; leaves open validation of individualized or serial monitoring.

Structured PICO

P
Population
9 healthy dogs
I
Intervention
Platelet function testing (TEG-PM, WBA, PFA) measured once every 7 days for 4 consecutive weeks
O
Outcome
Analytic and biologic variability of platelet function tests, and correlation between these variablessurrogate

Platelet function tests in healthy dogs show high biologic variability and poor correlation with one another, suggesting population-based reference intervals are inappropriate for most tests.

Cite This Study

Blois et al. (2015) studied this question.

synapsesocial.com/papers/69f69044e405cc4465bc2853https://doi.org/10.1111/vcp.12290
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