Why the study?
Does monitoring with the coagulation analyzer BCT and platelet function analyzer PFA-100 detect platelet inhibition in patients with arterial occlusive disease treated with aspirin or clopidogrel?
Population
125 consecutive patients with arterial occlusive disease
Design
Cohort
Authors
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BCT may enable clopidogrel monitoring where PFA-100 cannot in occlusive disease; leaves open whether testing improves outcomes.
Does monitoring with the coagulation analyzer BCT and platelet function analyzer PFA-100 detect platelet inhibition in patients with arterial occlusive disease treated with aspirin or clopidogrel?
The automated coagulation analyzer BCT can monitor platelet inhibition by both aspirin and clopidogrel, whereas the PFA-100 is only suitable for monitoring aspirin.
Mani et al. (2006) studied this question.
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