A higher PVC burden (>26%/day) and the presence of retrograde P-waves are independently associated with PVC-mediated left ventricular dysfunction in patients without structural heart disease.
AIMS: The mechanism responsible for premature ventricular complex (PVC)-mediated left ventricular (LV) dysfunction remains unclear. We sought to determine the electrocardiographic and electrophysiological characteristics of PVC-mediated LV dysfunction. METHODS AND RESULTS: One hundred and twenty-seven patients who underwent radiofrequency catheter ablation (RFCA) for frequent PVCs (PVCs burden ≥10%/24 h) and had no significant structural heart disease were investigated. Left ventricular dysfunction (ejection fraction 26%/day) and the presence of retrograde P-waves were independently associated with PVC-mediated LV dysfunction.
Ban et al. (Thu,) studied this question.