March 1, 2000Journal of Cardiovascular Electrophysiology215 citations
View Full PaperFirst Evidence of Premature Ventricular Complex‐Induced Cardiomyopathy: A Potentially Reversible Cause of Heart Failure
Structured PICO
Does radiofrequency ablation of frequent isolated PVCs improve left ventricular dysfunction in patients with PVC-induced cardiomyopathy?
P
Population
1 patient with dilated cardiomyopathy and frequent isolated premature ventricular complexes (PVCs)
I
Intervention
Radiofrequency ablation of the focal source of PVCs
O
Outcome
Resolution of dilated cardiomyopathy
This case provides the first evidence that frequent isolated PVCs can induce a reversible form of cardiomyopathy that resolves with radiofrequency ablation.
Abstract
Tachycardia-induced cardiomyopathy is a well-recognized and reversible condition, but left ventricular dysfunction due to frequent isolated premature ventricular complexes (PVCs) has not been reported. We observed resolution of dilated cardiomyopathy in a patient after a focal source of PVCs was eliminated by radiofrequency ablation. In a subset of patients with heart failure, PVC-induced cardiomyopathy may be a potentially reversible cause of left ventricular dysfunction.