March 1, 2000Journal of Cardiovascular Electrophysiology
First Evidence of Premature Ventricular Complex‐Induced Cardiomyopathy: A Potentially Reversible Cause of Heart Failure
Why the study?
Does radiofrequency ablation of frequent isolated PVCs improve left ventricular dysfunction in patients with PVC-induced cardiomyopathy?
Population
1 patient with dilated cardiomyopathy and frequent isolated premature ventricular complexes (PVCs)
Design
Case_report
Authors
Discussion
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Member takes
Implication
May support ablation for suspected PVC-induced cardiomyopathy; hypothesis-generating and requires prospective validation.
Key Points
- To report the first evidence of dilated cardiomyopathy and left ventricular dysfunction induced by frequent isolated premature ventricular complexes.
- Evaluated a patient presenting with dilated cardiomyopathy and frequent isolated premature ventricular complexes (PVCs).
- Eliminated the focal source of the PVCs using radiofrequency catheter ablation.
- Radiofrequency ablation successfully eliminated the focal source of premature ventricular complexes.
- Ablation of the PVC focus led to the complete resolution of dilated cardiomyopathy and reversed left ventricular dysfunction.
Structured PICO
Does radiofrequency ablation of frequent isolated PVCs improve left ventricular dysfunction in patients with PVC-induced cardiomyopathy?
P
Population
1 patient with dilated cardiomyopathy and frequent isolated premature ventricular complexes (PVCs)
I
Intervention
Radiofrequency ablation of the focal source of PVCs
O
Outcome
Resolution of dilated cardiomyopathy
This case provides the first evidence that frequent isolated PVCs can induce a reversible form of cardiomyopathy that resolves with radiofrequency ablation.
Cite This Study
Chugh et al. (2000) studied this question.