January 15, 1995Circulation
Comparison of Cardiopulmonary Adaptation During Exercise in Children After the Atriopulmonary and Total Cavopulmonary Connection Fontan Procedures
Why the study?
Does the TCPC Fontan procedure improve cardiopulmonary adaptation during exercise compared to the AP Fontan procedure in children?
Population
43 children studied more than 6 months after undergoing a Fontan procedure, and 106 healthy children as a…
Comparison
Total cavopulmonary connection Fontan procedure vs Atriopulmonary (AP) Fontan procedure
Design
Cross-sectional
Follow-up
>6 months post-procedure
Authors
Discussion
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Implication
May inform exercise physiology in Fontan variants without altering practice; leaves open optimal procedure choice pending longitudinal data.
Structured PICO
Does the TCPC Fontan procedure improve cardiopulmonary adaptation during exercise compared to the AP Fontan procedure in children?
P
Population
43 children studied more than 6 months after undergoing a Fontan procedure (23 atriopulmonary [AP] and 20 total cavopulmonary connection [TCPC]), and 106 healthy children as a control group.
I
Intervention
Total cavopulmonary connection (TCPC) Fontan procedure
C
Comparator
Atriopulmonary (AP) Fontan procedure
O
Outcome
Cardiopulmonary physiology during rest and exercise (effective pulmonary blood flow, stroke volume, arteriovenous oxygen difference, minute ventilation, heart rate, and oxygen and carbon dioxide consumption)surrogate
Children with a TCPC Fontan have superior pulmonary hemodynamics during submaximal exercise due to respiratory adaptation, whereas those with an AP Fontan rely on superior metabolic adaptation to achieve similar maximal exercise performance.
Cite This Study
Rosenthal et al. (1995) studied this question.