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December 23, 2017European Heart Journal - Cardiovascular ImagingOpen Access

Tricuspid regurgitation in acute heart failure: is there any incremental risk?

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Why the study?

Does moderate or severe tricuspid regurgitation increase the risk of readmission for heart failure or mortality in patients admitted for acute heart failure?

Population

639 patients admitted for acute heart failure

Comparison

Moderate or severe tricuspid regurgitation (TR) vs Trivial or mild tricuspid regurgitation (TR)

Design

Cohort

Authors

DMDiab MutlakJLJonathan LessickSKShehrban Khalil

Discussion

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Overview

Moderate/severe TR alone should not alter acute HF risk stratification; leaves open PH-stratified intervention trials.

Structured PICO

Does moderate or severe tricuspid regurgitation increase the risk of readmission for heart failure or mortality in patients admitted for acute heart failure?

P
Population
639 patients admitted for acute heart failure
I
Intervention
Moderate or severe tricuspid regurgitation (TR)
C
Comparator
Trivial or mild tricuspid regurgitation (TR)
O
Outcome
Composite of readmission for heart failure or mortalitycomposite

Significant tricuspid regurgitation in acute heart failure does not confer additive risk unless accompanied by pulmonary hypertension.

Cite This Study

Mutlak et al. (2017) studied this question.

synapsesocial.com/papers/69f69241c2e2af49314407f2https://doi.org/10.1093/ehjci/jex343
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Also Consider

Synapse has enriched one closely related paper. Consider it for comparative context:

  1. 1Impact of tricuspid regurgitation on survival in patients with chronic heart failure: unexpected findings of a long-term observational study2013 · 195 citations