PulseExploreJournal ClubDebatesTrendingResearchersJournals
Instagram
HomeExploreJournal ClubTrending
Synapse
⌘+K
Synapse
December 4, 2012Macromolecules225 citations

Application of 1H DOSY for Facile Measurement of Polymer Molecular Weights

View Full Paper
WLWeibin LiHCHoyong ChungCDChris Daeffler

Key Points

  • To establish an accurate, facile method for measuring polymer weight-average molecular weights across living/controlled polymerization systems using diffusion-ordered NMR spectroscopy (DOSY).
  • Generated external calibration curves based on the linear correlation between the logarithm of diffusion coefficient (log D) and the logarithm of molecular weight (log Mw).
  • Applied the calibration methodology to narrowly dispersed polymers synthesized via atom transfer radical polymerization (ATRP), reversible addition-fragmentation chain transfer (RAFT), and ring-opening metathesis polymerization (ROMP).
  • Successfully predicted weight-average molecular weights for narrowly dispersed polymers across ATRP, RAFT, and ROMP reaction systems.
  • Demonstrated that weight-average molecular weights calculated via DOSY linear calibration closely correlate with standard gel permeation chromatography (GPC) measurements.

Abstract

To address the practical issues of polymer molecular weight determination, the first accurate polymer weight-average molecular weight determination method in diverse living/controlled polymerization via DOSY (diffusion-ordered NMR spectroscopy) is reported. Based on the linear correlation between the logarithm of diffusion coefficient (log D) and the molecular weights (log Mw), external calibration curves were created to give predictions of molecular weights of narrowly-dispersed polymers. This method was successfully applied to atom transfer radical polymerization (ATRP), reversible addition-fragmentation chain transfer (RAFT), and ring-opening metathesis polymerization (ROMP), with weight-average molecular weights given by this method closely correlated to those obtained from GPC measurement.

Ask AI
Helpful
Bookmark
Share
View Full Paper

Cite This Study

Li et al. (2012) studied this question.

synapsesocial.com/papers/69f6aa1349562ccb3d7c66echttps://doi.org/10.1021/ma301666x
Ask AI
Helpful
Bookmark
Share
View Full Paper

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Real-Time Determination of Molecular Weight: Use of MaDDOSY (Mass Determination Diffusion Ordered Spectroscopy) to Monitor the Progress of Polymerization Reactions2024 · 22 citations
  2. 2Potential of Benchtop NMR for the Determination of Polymer Molar Masses, Molar Mass Distributions, and Chemical Composition Profiles by Means of Diffusion‐Ordered Spectroscopy, DOSY2024 · 3 citations
  3. 3Molar Mass Determination for Small and Large Molecules Using Diffusion-Ordered Spectroscopy2024 · 5 citations
  4. 4Models for molecular weight estimation using diffusion‐ordered NMR on poly(γ‐benzyl‐ <scp>l</scp> ‐glutamate) with low degrees of polymerization2026
  5. 5In-Line Molar Mass Determination in Semidilute Polymer Solutions2026