Prediction of relapsed/refractory primary central nervous system lymphoma using pre-chemotherapy ITSS grade on SWI and pre-/post-chemotherapy ADC parameters on DWI.

OBJECTIVES: The purpose of this study was to evaluate the role of SWI and DWI in predicting the relapsed/refractory primary central nervous system lymphoma (R/R PCNSL). MATERIALS AND METHODS: ), were compared between the two groups. Receiver operating characteristic curves and logistic regression analysis were used to assess the predictive performance. RESULTS: was comparable to that of pre-chemotherapy ITSS grade for R/R PCNSL (0.894 vs. 0.714, 0.867 vs. 0.714, 0.877 vs. 0.714, 0.814 vs. 0.714, all P > 0.05), but superior to that of Ki-67 index (0.894 vs. 0.665, 0.867 vs. 0.665, 0.877 vs. 0.665, 0.814 vs. 0.665, all P < 0.05). CONCLUSIONS: may serve as preferable imaging biomarkers for predicting R/R PCNSL, and compare favorably with Ki-67 index.