Demonstrates the role of Irf7 signaling in olfactory dysfunction, suggesting new targets for treatment.
) was observed to be associated with mitigation of these effects. Together, these findings are consistent with a proposed adverse outcome pathway (AOP) framework that suggests a link between the EtCBN-Irf7 interaction and LCM-associated neurotoxicity, offering potential mechanistic insights and therapeutic targets for olfactory dysfunction.
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Duan et al. (2026) studied this question.
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