Colonization and Acquisition of Carbapenem-Resistant and Carbapenemase-Producing Enterobacterales Among Hospitalized Adult Patients in Addis Ababa, Ethiopia.

Dessie Abera; Woldaregay Erku Abegaz; Abel Abera Negash; Adane Mihret

doi:10.1177/10766294261445545

April 30, 2026

Colonization and Acquisition of Carbapenem-Resistant and Carbapenemase-Producing Enterobacterales Among Hospitalized Adult Patients in Addis Ababa, Ethiopia.

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Key Points

This research aims to assess the colonization and acquisition rates of carbapenem-resistant and carbapenemase-producing Enterobacterales among hospitalized adults.
Patients were screened for carbapenem-resistant Enterobacterales at admission and during follow-up.
Follow-up assessments determined the persistence rates of these bacteria in high-risk patients.
Emphasis was placed on enhancing infection prevention protocols based on findings.
At admission, 53.0% of patients were colonized with carbapenem-resistant Enterobacterales.
During follow-up, detection rates were 74.1% for carbapenem-resistant and 48.1% for carbapenemase-producing strains.
Findings indicate a substantial burden of CRE and CP-CRE colonization with a high persistence rate.

Implication

Uncovers a high burden of carbapenem-resistant Enterobacterales in hospitalized adults, indicating urgent need for infection control measures.

Abstract

(53.0%) at admission. These genes were detected in (74.1%) and (48.1%) during follow-up, respectively. A substantial burden of CRE and CP-CRE colonization was found, with a high persistence rate. Screening high-risk patients and strengthening infection prevention measures are urgently needed.

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Cite This Study

Abera et al. (2026) studied this question.

synapsesocial.com/papers/69f6e60f8071d4f1bdfc6b1d https://doi.org/10.1177/10766294261445545

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Colonization and Acquisition of Carbapenem-Resistant and Carbapenemase-Producing Enterobacterales Among Hospitalized Adult Patients in Addis Ababa, Ethiopia.

Key Points

Implication

Abstract

Discussion

Cite This Study

Colonization and Acquisition of Carbapenem-Resistant and Carbapenemase-Producing Enterobacterales Among Hospitalized Adult Patients in Addis Ababa, Ethiopia.

Key Points

Implication

Abstract

Discussion

Cite This Study

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