Observational cohort reports low relapse and switch rates in deep-seated infections, indicating feasibility of outpatient therapy.
Following the COPAT randomized trial demonstrating improved safety with early outpatient oral antibiotics, we report outcomes from such a clinic in Singapore. In this observational cohort of deep-seated infections, we found that relapse of infection and oral-to-intravenous antibiotic switch were uncommon, supporting feasibility of this approach in the real-world setting.
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Foo et al. (2026) studied this question.
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