The aim is to explore a metal-free Minisci C-H alkylation process for synthesizing hydrazone-containing pyrimidine derivatives using aldehydes.
Utilized aldehydes for C-H alkylation of hydrazones
Implemented a method involving trifluoroacetic acid
Focused on synthesizing structurally diverse heterocyclic compounds.
Successfully developed a scalable metal-free method for the synthesis of pyrimidine derivatives
Demonstrated practicality for accessing a variety of structurally heterocyclic compounds.
Abstract
and trifluoroacetic acid (TFA). This method provides a practical and scalable approach to accessing structurally heterocyclic compounds of various classes.