Utility of α-halodicyclopentadienones for the synthesis of novel fused heterocycles

Key Points

• The aim is to explore the utility of α-halodicyclopentadienones in creating new fused heterocycles.
• Base-mediated Michael addition of amidines to α-halodicyclopentadienones
• Cyclization of intermediate Michael adducts to form fused tetracycles and hexacycles
• Assessment of diastereoselectivity in cyclization products.
• Produced linear fused tetracycles to hexacycles
• Achieved complete diastereoselectivity in the reaction outcome.